Cancer Biology Department

Title: Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types ORCID

Authors: Cijo George Vazhappilly, Ekram Saleh, Wafaa Ramadan, Varsha Menon, Aya Mudhafar Al-Azawi, Hamadeh Tarazi, Hajjaj Abdu-Allah, Abdel-Nasser El-Shorbagi, Raafat El-Awady

Year: 2019 | Journal: Investigational New Drugs | DOI: 10.1007/s10637-018-0626-5

Title: Novel CYP1B1 mutations and a possible prognostic use for surgical management of congenital glaucoma ORCID

Authors: Khafagy, M.M., El-Guendy, N., Tantawy, M.A., Eldaly, M.A., Elhilali, H.M., Abdel Wahab, A.H.A.

Year: 2019 | Journal: International Journal of Ophthalmology | DOI: 10.18240/ijo.2019.04.14

Title: Synthesis and biochemical studies of novel organic selenides with increased selectivity for hepatocellular carcinoma and breast adenocarcinoma ORCID

Authors: Shaaban, S., Ashmawy, A.M., Negm, A., Wessjohann, L.A.

Year: 2019 | Journal: European Journal of Medicinal Chemistry | DOI: 10.1016/j.ejmech.2019.06.075

Title: Chemical Composition of Aqueous Ethanol Extract of Luffa cylindrica Leaves and Its Effect on Representation of Caspase-8, Caspase-3, and the Proliferation Marker Ki67 in Intrinsic Molecular Subtypes of Breast Cancer in Vitro ORCID

Authors: Abdel-Salam, I.M., Ashmawy, A.M., Hilal, A.M., Eldahshan, O.A., Ashour, M.

Year: 2018 | Journal: Chemistry and Biodiversity | DOI: 10.1002/cbdv.201800045

Title: Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line ORCID

Authors: Zaki, I., Abdelhameid, M.K., El-Deen, I.M., Abdel Wahab, A.H.A., Ashmawy, A.M., Mohamed, K.O.

Year: 2018 | Journal: European Journal of Medicinal Chemistry | DOI: 10.1016/j.ejmech.2018.07.003

Title: Inhibition of exosome release by ketotifen enhances sensitivity of cancer cells to doxorubicin ORCID

Authors: Farman Matloob Khan, Ekram Saleh, Hussain Alawadhi, Rania Harati, Wolfram-Hubertus Zimmermann, Raafat El-Awady

Year: 2018 | Journal: Cancer Biology & Therapy | DOI: 10.1080/15384047.2017.1394544

Title: Interplay between Epigenetics, Expression of Estrogen Receptor- ?, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy ORCID

Authors: Wafaa S Ramadan, Cijo George Vazhappilly, Ekram M Saleh, Varsha Menon, Aya M AlAzawi, Ahmed T El-Serafi, Wael Mansour, Raafat El-Awady

Year: 2018 | Journal: Cancers | DOI: 10.3390/cancers11010013

Title: MicroRNA Signatures for circulating CD133-positive cells in hepatocellular carcinoma with HCV infection ORCID

Authors: Zekri, A.-R.N., El-Sisi, E.R., El-Din Youssef, A.S., Kamel, M.M., Nassar, A., Ahmed, O.S., El Kassas, M., Barakat, A.B., El-Motaleb, A.I.A., Bahnassy, A.A.

Year: 2018 | Journal: PLoS ONE | DOI: 10.1371/journal.pone.0193709

Title: MiRNAs as molecular biomarkers in stage II egyptian colorectal cancer patients ORCID

Authors: Bahnassy, A.A., Salem, S.E., El-Sayed, M., Khorshid, O., Abdellateif, M.S., Youssef, A.S., Mohanad, M., Hussein, M., Zekri, A.-R.N., Ali, N.M.

Year: 2018 | Journal: Experimental and Molecular Pathology | DOI: 10.1016/j.yexmp.2018.09.002

Title: Circulating microRNAs panel as a diagnostic tool for discrimination of HCV-associated hepatocellular carcinoma ORCID

Authors: Ali, H.E.A., Abdel Hameed, R., Effat, H., Ahmed, E.K., Atef, A.A., Sharawi, S.K., Ali, M., Abd Elmageed, Z.Y., Abdel Wahab, A.H.

Year: 2017 | Journal: Clinics and Research in Hepatology and Gastroenterology | DOI: 10.1016/j.clinre.2017.06.004