Bone Marrow transplantation Lab Unit

(BMT Lab Unit)

(4 Subunits)

In charge of advanced laboratory techniques:

         routine, teaching, training and research

1- Flow Cytometry

2- Molecular Genetics

3-  Immunogenetics

4- Pharmacogenomics

 

A: BMT Lab Unit Activities: Routine services

      Free for NCI patients, others are charged

B: BMT Lab Unit Activities: Teaching

·         Participate in the Academic teaching (theoretical and practical)for candidates of MD in Clinical Pathology and Oncologic Laboratory Medicine at NCI:

·         Participate in the Academic teaching for candidates of Other M SC and MD degrees in the NCI

C: BMT Lab Unit Activities: Training 

I- Training of individual candidates

  • Candidates from other institutions:  South Valley Cancer Institute and other Cancer Institutes, Menofeya Faculty of Medicine.

  • Non-Egyptians: Jordanian, Iraqi, Sudanese, Libyan

 

II- Workshops Organized 

  • Seven workshops on Flow Cytometry organized on   regular basis  in collaboration with International Expertise: 1995, 96, 99, 2001, 2004, 2006 and 2008

D: BMT Lab Unit Activities: Research 

I- Supervision of MD and M Sc theses:

·         Supervising MD in Clinical Pathology and Oncologic Laboratory Medicine at the NCI, Cairo University:

                     NCI Registrars (Ass.  Lecturer)

                     Military Hospitals

                     Ministry of Health

·         Supervising M SC and MD degrees of other specialties at the NCI, Cairo University

·         Supervising candidates from other Universities: Faculties of Medicine, Cairo, Menofeya, Zagazig  & Ain- Shams, Research Center, South Valley Cancer Institute and other Cancer Institutes, Faculty of Science, Cairo University and Helwan University

 

II- Research projects

 

A- Current Projects

  1. Preparation for accreditation of Bone Marrow Transplantation Laboratory Unit at National Cancer Institute. HEI Labs Certification Project LP3-027-CAI, Program of Continuous Improvement and Qualification for Accreditation in HEI, Ministry of Higher Education.                                                                             Director: Dean of NCI, Executive director: Azza M kamel                                                           Egyptian PI: Azza M Kamel, US PI: John Hansen

  1. Fusion gene transcript levels at diagnosis and their kinetics in response to therapy as prognostic indicators in acute leukemia. A conjoint project between NCI, Cairo University and St. Jude Children's Hospital, Memphis, USA. US-Egypt Joint Fund. ID-code: BIO11-002-013.                                                                      Egyptian PI: Azza M kamel, US PI: Sheila Shurtlef

  1. Role of Non-HLA Genes Polymorphisms in Predicting the Outcome of HLA Matched Sibling Bone Marrow Transplantation, funded by Cairo University.                                                                                             PI: Azza M kamel, Co-PI: Gamal TA Ebid

 B- Completed Projects

  1. Study of variable number tandem repeats as a tool for detection of chimerism after allogeneic BMT, Cairo University. PI: Azza M kamel

  2. Molecular genetics of pediatric ALL in Egypt as a potential risk factor; a conjoint project between NCI, Cairo University and St. Jude Children's Hospital, Memphis, USA. US-Egypt Joint Fund. ID-code: BIO6-002-002, contract No.: 150

    Egyptian PI: Azza M kamel, US PI: Sheila Shurtlef

    Quantitative evaluation of chimerism post allogeneic stem cell transplantation: possible impact on clinical decision. A conjoint project between NCI, Cairo University and Fred Hutchinson Cancer Center, Seattle, Washington, USA: US-Egypt Joint Fund. ID-code: BIO7-002-002, contract No 188.

    Egyptian PI: Azza M kamel, US PI: Paul Martin

  1. The role of cytokines in the pathogenesis of graft versus host disease after allogeneic peripheral blood stem cell transplantation. A conjoint project between NCI, Cairo University and Roswell Park Cancer Institute, Buffalo, NY USA. US-Egypt Joint Fund. ID-code: BIO8-002-002, contract No 224.

    Egyptian PI: Azza M kamel, US PI: Paul Wallace

  1. Genetics of Juvenile Type 1 Diabetes in Egypt. A conjoint project between NCI / Pediatric Hospital, Faculty of Medicine, Cairo University and Fred Hutchinson Cancer Center, Seattle, Washington, USA. US-Egypt Joint Fund. ID-code: BIO9-002-010, contract No 268. ,

    Egyptian PI: Azza M kamel, US PI: John Hansen

  1. Polymorphisms in the Genes of drug metabolizing enzymes and the prediction of drug response and toxicity to cancer chemotherapy in Egyptian patients, funded by Cairo University PI: Gamal TA Ebid

  2. Wilms’ tumor gene as a panleukemic marker in minimal residual disease detection, funded by Cairo University PI: Ghada Mossallam